It can indicate if there is any kidney damage. The higher the filtration rate, the better the kidneys are working. If your doctor orders a blood test to learn more about your kidney function, an eGFR result is provided automatically, along with your creatinine results.
Your doctor may also test for other signs and conditions that may indicate you have chronic kidney disease.
These may include tests for:. Well-functioning kidneys are essential to your overall health. Early detection of kidney disease can be life-saving. Medication and changes to lifestyle, along with an early referral to a kidney specialist, can prevent or delay kidney failure. If you are at increased risk of chronic kidney disease , talk to your doctor about having a regular kidney health check.
This page has been produced in consultation with and approved by:. Bedwetting is a problem for many children and punishing them for it will only add to their distress. Your bladder is a hollow organ that stores urine from the kidneys. Bladder cancer affects twice as many men as women.
Bladder prolapse is when the bladder bulges into the vagina. Cystitis is the most common urinary tract infection in women.
Given that no new nephrons are formed in human kidneys after approximately 36 weeks' gestation, much interest has focused on renal function and health in individuals born with relatively low nephron endowment. Several studies have reported a direct correlation between birth weight and nephron number and an indirect association between nephron number and blood pressure. Learning Objectives Explain the role of the nephron as the functional unit of the kidney.
Key Points Kidneys contain two types of nephrons, each located in different parts of the renal cortex: cortical nephrons and juxtamedullary nephrons. A nephron comprises a renal corpuscle, a renal tubule, and the associated capillary network. Internally, kidneys are mainly composed of over one million nephrons and an extensive network of blood vessels and capillaries.
Indeed, a single kidney with only 75 percent of its functional capacity can sustain life very well. This overengineering supplies us with 1. Nephrons are tiny tubes that filter the blood plasma, adjust and then return optimized fluid to the body.
Under most conditions, though totaling only a few pounds, the kidneys receive about 20 percent of all the blood pumped from the heart. Each day, about liters of fluid and particles enter into the nephron to be filtered. If only one kidney is present, that kidney can adjust to filter as much as two kidneys would normally. In such a situation, the nephrons compensate individually by increasing in size--a process known as hypertrophy--to handle the extra load. This happens with no adverse effects, even over years.
In fact, if one functional kidney is missing from birth, the other kidney can grow to reach a size similar to the combined weight of two kidneys about one pound. The kidneys filter this large amount of fluid on a daily basis because nephrons are fairly indiscriminant filters, removing all contents from the blood except for larger proteins and cells.
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